2025/04/08 by Skyler Berardi, Jessica A. Rhodes, M. Berner +8 · 2 voices · 8 citations
Biochemistry, Genetics and Molecular Biology · #Biology #Computational biology #Computer science #Drosophila (subgenus) #Drosophila melanogaster #Evolution and Genetic Dynamics #Evolutionary biology #Gene #Genetic Mapping and Diversity in Plants and Animals #Genetic diversity and population structure #Genetics #Parallel computing #Parallel evolution #Parallelism (grammar) #Phenotype #Phylogenetics
paper · pdf · doi:10.1093/evlett/qraf008
published in Evolution Letters 9(4), 408-420 (Wiley)
openalex publication_date 2025/04/08 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
Abstract Populations are capable of responding to environmental change over ecological timescales via adaptive tracking. However, the translation from patterns of allele frequency change to rapid adaptation of complex traits remains unresolved. We used abdominal pigmentation in Drosophila melanogaster as a model phenotype to address the nature, genetic architecture, and repeatability of rapid adaptation in the field. We show that D. melanogaster pigmentation evolves as a highly parallel and deterministic response to shared environmental variation across latitude and season in natural North American populations. We then experimentally evolved replicate, genetically diverse fly populations in field mesocosms to remove any confounding effects of demography and/or cryptic structure that may drive patterns in wild populations; we show that pigmentation rapidly responds, in parallel, in fewer than 15 generations. Thus, pigmentation evolves concordantly in response to spatial and temporal climatic axes. We next examined whether phenotypic differentiation was associated with allele frequency change at loci with established links to genetic variance in pigmentation in natural populations. We found that across all spatial and temporal scales, phenotypic patterns were associated with variation at pigmentation-related loci, and the sets of genes we identified at each scale were largely nonoverlapping. Therefore, our findings suggest that parallel phenotypic evolution is associated with distinct components of the polygenic architecture shifting across each environmental axis to produce redundant adaptive patterns.