Simulation of Particle Release for Diffusing Alpha-Emitters Radiation Therapy

2022/11/25 by Fedorchenko, Dmytro, Shlomi Alani, Alani, Shlomi
Medicine · Physics and Astronomy · #Advanced Radiotherapy Techniques #Computational Physics (physics.comp-ph) #FOS: Physical sciences #Medical Imaging Techniques and Applications #Medical Physics (physics.med-ph) #Radiopharmaceutical Chemistry and Applications

paper · pdf · doi:10.48550/arxiv.2211.14071

openalex publication_date 2022/11/25 · openalex created_date 2022/11/30 · openalex updated_date 2026/07/28

Abstract

We used Monte Carlo simulations to study release of radium-224 daughter nuclei from the seed used for Diffusing Alpha-Emitters Radiation Therapy (DART). Calculated desorption probabilities for polonium-216 (15%) and lead-212 (12%) show that they make a significant contribution to total release from the seed. We also showed that the dose to tissue from decays inside the 10mm long seed exceeds 2.9 Gy for initial radium-224 activity of 111 kBq.

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