2025/07/22 by Jing Hu, Tianjian Lv, Hu, Jing +8
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #FOS: Physical sciences #Ocular and Laser Science Research #Optics (physics.optics) #Random lasers and scattering media #Spectroscopy Techniques in Biomedical and Chemical Research
paper · pdf · doi:10.48550/arxiv.2507.16161
openalex publication_date 2025/07/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Broadband coherent anti-Stokes Raman scattering (CARS) spectroscopy plays a vital role in chemical sensing and label-free vibrational imaging, yet conventional methods suffer from limited acquisition speeds and complex detection schemes. Here, we demonstrate high-speed broadband CARS enabled by nonlinear spectral ghost imaging combined with time-stretch dispersive Fourier-transform spectroscopy (TS-DFT). We exploit modulation instability to generate a stochastic supercontinuum as the Stokes source and a synchronized narrowband pulse as the pump. Reference Stokes spectra are captured at 60.5 MHz via TS-DFT, while anti-Stokes signals are detected using a single non-spectrally resolving photodetector. Correlating these signals enables broadband CARS spectral reconstruction across the fingerprint (600-1600 cm-1) and C-H stretching (2600-3400 cm-1) regions with 13 cm-1 resolution and microsecond-scale acquisition times. Our method enables robust signal recovery without the need for spectral resolution in the detection path, facilitating measurements in complex biological and chemical environments.