Selection of parameters for thermal coronavirus inactivation – a data-based recommendation

2020/07/13 by Martin Heßling, Hessling, Martin, Katharina Hoenes +3
Medicine · #610 Medical sciences #COVID-19 Clinical Research Studies #Coronavirus #Hitze #Infection Control and Ventilation #MERS-CoV #Medicine #SARS-CoV #SARS-CoV-2 #SARS-CoV-2 and COVID-19 Research #Sterilisation #coronavirus #heat #sterilization #thermal inactivation #thermische Inaktivierung

paper · doi:10.3205/dgkh000351

openalex publication_date 2020/07/13 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/19

Abstract

Coronaviruses can already be inactivated at relatively low temperatures. For most samples, application times of approximately 32.5, 3.7, and 0.5 minutes will be sufficient at 60°C, 80°C, and 100°C, respectively, for a 5 log-reduction. For difficult conditions, the worst-case model provides significantly longer application times of 490, 55, and 8 minutes for the temperatures mentioned.

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