2011/11/23 by Jau-Yi Wang, Patrick Mesquida, Wang, Jau-Yi +9
Engineering · Medicine · Physics and Astronomy · #Biological Physics (physics.bio-ph) #FOS: Physical sciences #Inhalation and Respiratory Drug Delivery #Medical Physics (physics.med-ph) #Metal and Thin Film Mechanics #Shoulder Injury and Treatment #physics.bio-ph #physics.med-ph
paper · pdf · doi:10.48550/arxiv.1111.5645
8 pages, 5 figures
arxiv created 2011/11/23 · openalex publication_date 2011/11/23 · arxiv updated 2011/11/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Young's Modulus and dynamic force moduli were measured on human bronchial airway tissues by compression. A simple and low-cost system for measuring the tensile-strengh of soft bio-materials has been built for this study. The force-distance measurements were undertaken on the dissected bronchial airway walls, cartilages and mucosa from the surgery-removed lungs donated by lung cancer patients with COPD. Young's modulus is estimated from the initial slope of unloading force-displacement curve and the dynamic force moduli (storage and loss) are measured at low frequency (from 3 to 45 Hz). All the samples were preserved in the PBS solution at room temperature and the measurements were perfomed within 4 hours after surgery. Young's modulus of the human bronchial airway walls are fond ranged between 0.17 and 1.65 MPa, ranged between 0.25 to 1.96 MPa for cartilages, and between 0.02 to 0.28 MPa for mucosa. The storage modulus are found varying 0.10 MPa with frequency while the loss modulus are found increasing from 0.08 to 0.35 MPa with frequency. The frequency-dependent dynamic force moduli are also compared with different strain rates.