The alpha tubulin acetyltransferase atat-2 genetically interacts with klp-4 in C. elegans

2025/02/10 by Claire E. Reist, Michael D. Webb, Cortlen M Mathews +1
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer-related Molecular Pathways #Microtubule and mitosis dynamics #Ubiquitin and proteasome pathways

paper · doi:10.17912/micropub.biology.001536

openalex publication_date 2025/02/10 · openalex created_date 2025/04/29 · openalex updated_date 2026/07/01

Abstract

lays the foundation of future work on these two parallel, yet related processes in cells.

Related

• Microtubule damage shapes the acetylation gradient
• Mutating different α-tubulin acetylation sites has distinct effects on axon terminal morphogenesis in Drosophila melanogaster
• PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans
• Tubulin acetylation deficiency promotes axonemal turnover and increases cytoplasmic microtubules
• Kinesin-12 KLP-18 contributes to the kinetochore-microtubule poleward flux during the metaphase of C. elegans one-cell embryo