Mini Review on synthetic methods and biological activities of various substituted pyrimidine derivatives

2016/08/01 by Mohammad Asif, Asif, Mohammad
Chemistry · #Multicomponent Synthesis of Heterocycles #Pyrimidines #Synthesis and Characterization of Heterocyclic Compounds #Synthesis and biological activity #biological activities #heterocycle #synthesis

paper · doi:10.48317/imist.prsm/morjchem-v4i4.5937

openalex publication_date 2016/08/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/01

Abstract

Pyrimidines are versatile nitrogen containing heterocyclic compounds, possessing various types of biological and pharmacological activities like antimicrobial, hypotensive, antimalerial, antidepressant, antitubercular, anticoagulant, hypnotic, fungicidal, anti-inflammatory, analgesic, antiulcer, antiviral and anticancer and other useful activities. Pyrimidine nucleus is endowed with a variety of therapeutic activities and new Pyrimidine are known to be biologically active compounds possessing several pharmacological activities Pyrimidines aroused our interest in synthesizing new Pyrimidines nucleus featuring different substitution with more potent pharmacologically active compounds.

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