Cyclization of some N-Arylidene-2-(Acetamido)-3-(4-Chlorophenyl)Acrylohydrazides to 1-Arylideneamino-4-(4-Chlorobenzylidene)-2-Methyl-1h-Imidazolin-5(4h)-Ones

2020/09/13 by Nguyen, Cong Tien, Nguyen, Thanh Thi, Nguyen, Thanh Van +1
#1-arylideneamino-4-(4-chlorobenzylidene)-2-methyl-1H-imidazolin-5(4H)-one #N-substituted hydrazide #cyclization #spectral data

paper · doi:10.48317/imist.prsm/morjchem-v4i3.4885

Abstract

Cyclization of the N-arylidene-2-(acetamido)-3-(4-chlorophenyl)acrylohydrazides, which were prepared from 4-chlorobenzaldehyde and acetylglycine via 4-chlorobenzylidene-2-methyl-(4H)-oxazol-5-one and then 2-(acetamido)-3-(4-chlorophenyl)acrylohydrazide, on treatment with acetic anhydride gave seven corresponding compounds namely 1-arylideneamino-4-(4-chlorobenzylidene)-2-methyl-1H-imidazolin-5(4H)-ones but did not give 3-acetyl-2-aryl-5-[1-acetamido-2-(4-chlorophenyl)vinyl]-1,3,4-oxadiazolines. The structure of the imidazoline-5-one compounds was confirmed by IR, 1H-NMR and MS spectral data.

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