2011/12/06 by Abdelwahed Barkaoui, Barkaoui, Abdelwahed, Ridha Hambli +1
Engineering · Medicine · Physics and Astronomy · #Bone health and osteoporosis research #FOS: Physical sciences #Medical Imaging Techniques and Applications #Medical Imaging and Analysis #Medical Physics (physics.med-ph) #physics.med-ph
paper · pdf · doi:10.48550/arxiv.1112.1184
MMM2010, freiburg : Germany (2010)
arxiv created 2011/12/06 · openalex publication_date 2011/12/06 · arxiv updated 2011/12/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Complexity and heterogeneity of bone tissue require a multiscale modelling to understand their mechanical behaviour and their remodelling mechanism. Human cortical bone structure consists of six structural scale levels which are the (macroscopic) cortical bone, osteonal, lamellar, fibrous, fibril and microfibril. In this paper, a 3D model based on finite elements method was achieved to study the nanomechanical behaviour of collagen Microfibril. The mechanical properties and the geometry (gap, overlap and diameter) of both tropocollagen and mineral were taken into consideration as well as the effects of cross-links. An inverse identification method has been applied to determine equivalent averaged properties in order to link up these nanoscopic characteristics to the macroscopic mechanical behaviour of bone tissue. Results of nanostructure modelling of the nanomechanical properties of strain deformation under varying cross-links were investigated in this work.