2024/10/22 by Noohi, Ghafar, Mamaghani, Manouchehr, Rezaei, Iman +1
#Bis-triazole #MoS2 #Nanoparticle #Triazole #Zinc #γ-Fe2O3
paper · doi:10.57647/j.ijc.2024.1404.37
ABSTRACT Triazoles are an important group that have active biological properties, and their synthetic platform and reactions have been fully investigated by many synthetic and medicinal chemists during the recent years. Magnetic nanocatalysts have recently been used in the design of many reactions, so in this method, an efficient, novel, and recyclable magnetic nanocatalyst γ-Fe2O3@MoS2@Zn was synthesized by the reaction of premade g-Fe2O3@MoS2 and ZnCl2 to furnish the desired nanocatalyst which was characterized by using FT-IR, XRD, SEM, EDX, TEM, mapping and VSM techniques. The catalyst was used in the synthesis of mono- and bis-triazoles by the reaction of thiosemicarbazide or butane-1,4-diyl-bis(hydrazinecarbimidothioate) with various arylaldehydes at room temperature and in ethanol/water (50:50) as solvent. This novel protocol gave the desired products excellent yields (92-96%) and lower reaction times (15-20 min). The synthesized magnetic nanoparticles were comfortability separated from the reaction mixture by means of an external magnet and employed in six consecutive runs without any significant changes in its catalytic activity. The advantages of this current method are short reaction time, excellent efficiency, use of green solvent, magnetic nanocatalyst, and cost-effectiveness.