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Bubble Gating Currents in Ionic Channels

2008/02/03 by Bob Eisenberg, Eisenberg, Bob
Biochemistry, Genetics and Molecular Biology · Engineering · #Advanced Memory and Neural Computing #Microfluidic and Capillary Electrophoresis Applications #Semiconductor materials and devices #q-bio.BM #q-bio.QM

paper · pdf · doi:10.48550/arxiv.0802.0308

Typo corrected

arxiv created 2008/02/05 · arxiv updated 2009/12/01

Abstract

Bubbles in ion channel proteins have been proposed to be the bistable gates that control current flow. Gating currents associated with channel gating would then be an electrical signature of bubble breaking and formation, arising from the change in dielectric coefficient as the bubble breaks or forms. A bubble would have a dielectric coefficient of 1. A filled bubble would have a dielectric coefficient (say) between 30 and 80. Transporters, pumps, and channels would be expected to have gating currents.

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