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Hybrid-View Attention Network for Clinically Significant Prostate Cancer Classification in Transrectal Ultrasound

2025/07/04 by Zetian Feng, Juan Fu, Feng, Zetian +11
Computer Science · Medicine · #AI in cancer detection #Advanced Neural Network Applications #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Prostate Cancer Diagnosis and Treatment #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2507.03421

openalex publication_date 2025/07/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Prostate cancer (PCa) is a leading cause of cancer-related mortality in men, and accurate identification of clinically significant PCa (csPCa) is critical for timely intervention. Transrectal ultrasound (TRUS) is widely used for prostate biopsy; however, its low contrast and anisotropic spatial resolution pose diagnostic challenges. To address these limitations, we propose a novel hybrid-view attention (HVA) network for csPCa classification in 3D TRUS that leverages complementary information from transverse and sagittal views. Our approach integrates a CNN-transformer hybrid architecture, where convolutional layers extract fine-grained local features and transformer-based HVA models global dependencies. Specifically, the HVA comprises intra-view attention to refine features within a single view and cross-view attention to incorporate complementary information across views. Furthermore, a hybrid-view adaptive fusion module dynamically aggregates features along both channel and spatial dimensions, enhancing the overall representation. Experiments are conducted on an in-house dataset containing 590 subjects who underwent prostate biopsy. Comparative and ablation results prove the efficacy of our method. The code is available at https://github.com/mock1ngbrd/HVAN.

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