Stability analysis and optimal control of an HIV/AIDS epidemic model

2023/04/17 by Nouar Chorfi, Chorfi, Nouar, Salem Abdelmalek +3
Mathematics · Medicine · Social Sciences · #COVID-19 epidemiological studies #Dynamical Systems (math.DS) #Evolutionary Game Theory and Cooperation #FOS: Mathematics #Mathematical and Theoretical Epidemiology and Ecology Models

paper · pdf · doi:10.48550/arxiv.2304.08251

openalex publication_date 2023/04/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

In this article, we consider an HIV/AIDS epidemic model with four classes of individuals. We have discussed about basic properties of the system and found the basic reproduction number R₀ of the system. The stability analysis of the model shows that the system is locally as well as globally asymptotically stable at disease-free equilibrium E₀ when R₀<1. When R₀>1 endemic equilibrium E₁ exists and the system becomes locally asymptotically stable at E₁. An optimal controller is presented that considers the use of three different measures to combat the spread of HIV/AIDS, namely: the use of condoms, screening of unaware infective individuals, and treatment of the HIV infected population. The objective of the optimal controller is to minimize the size of the susceptible and infected populations. Our investigation of the controlled system starts with establishing the existence of the optimal control, followed by identifying the necessary conditions of optimality.

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