2018/03/08 by Fardin Khalili, Khalili, Fardin, Peshala Thibbotuwawa Gamage +5
Medicine · Physics and Astronomy · #Cardiac Valve Diseases and Treatments #Cardiology #Composite material #Computational fluid dynamics #Coronary Interventions and Diagnostics #Dysfunctional family #FOS: Physical sciences #Fluid Dynamics (physics.flu-dyn) #Heart valve #Hemodynamics #Internal medicine #Materials science #Mechanical heart #Mechanics #Medicine #Physics #Shear (geology) #Shear stress #Turbulence #Venous Thromboembolism Diagnosis and Management #physics.flu-dyn
paper · pdf · doi:10.48550/arxiv.1803.03361
published in arXiv (Cornell University) (Cornell University)
openalex publication_date 2018/03/08 · arxiv created 2018/03/09 · arxiv updated 2018/03/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
There are more than 300,000 heart valves implanted annually worldwide with\nabout 50% of them being mechanical valves. The heart valve replacement is often\na common treatment for severe valvular disease. However, valves may dysfunction\nleading to adverse hemodynamic conditions. The current computational study\ninvestigated the flow around a bileaflet mechanical heart valve at different\nleaflet dysfunction levels of 0%, 50%, and 100%, and documented the relevant\nflow characteristics such as vortical structures and turbulent shear stresses.\nStudying the flow characteristics through these valves during their normal\noperation and dysfunction can lead to better understanding of their\nperformance, possibly improved designs, and help identify conditions that may\nincrease the potential risk of blood cell damage. Results suggested that\nmaximum flow velocities increased with dysfunction from 2.05 to 4.49 ms-1 which\nwere accompanied by growing eddies and velocity fluctuations. These\nfluctuations led to higher turbulent shear stresses from 90 to 800 N.m-2 as\ndysfunctionality increased. These stress values exceeded the thresholds\ncorresponding to elevated risk of hemolysis and platelet activation. The\nregions of elevated stresses were concentrated around and downstream of the\nfunctional leaflet where high jet velocity and stronger helical structures\nexisted.\n