2024/10/23 by Mouqing Zhou, Baohua Xu, Zhou, Mouqing +10
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Antibiotic Resistance in Bacteria #Antibiotic Use and Resistance #Nosocomial Infections in ICU
paper · doi:10.3205/dgkh000506
Background: (CA-MDRPa). We quantitatively modeled the incidence rate and clinical factors associated with CA-MDRPa among hospitalized patients in Southern China. Methods: Data were obtained from the local nosocomial surveillance system. Poisson regression was applied to estimate annual incidence rate ratios (IRRs) from 2018 to 2021. After propensity-score 1:2 matching, multivariable conditional logistic regression was used to identify factors for CA-MDRPa upon admission and adverse clinical outcomes during hospitalization. Results: acquisition during hospitalization (odds ratio [OR], 2.70; 95% CI, 1.53-4.77) and increased in-hospital mortality (OR, 2.24; 95% CI, 1.17-4.28). Conclusions: The findings emphasize the importance of regular targeted screening for CA-MDRPa upon hospital admission and offer valuable insights for strengthening infection control and antimicrobial stewardship programs.