Air pollution and cardiovascular disease: car sick
2019/08/20 by Mark R Miller, Mark R. Miller, David E. Newby +1 · 29 citations
Environmental Science · Engineering · #Air Quality and Health Impacts #Vehicle emissions and performance #Air Quality Monitoring and Forecasting
paper · pdf · doi:10.1093/cvr/cvz228
Abstract
The cardiovascular effects of inhaled particle matter (PM) are responsible for a substantial morbidity and mortality attributed to air pollution. Ultrafine particles, like those in diesel exhaust emissions, are a major source of nanoparticles in urban environments, and it is these particles that have the capacity to induce the most significant health effects. Research has shown that diesel exhaust exposure can have many detrimental effects on the cardiovascular system both acutely and chronically. This review provides an overview of the cardiovascular effects on PM in air pollution, with an emphasis on ultrafine particles in vehicle exhaust. We consider the biological mechanisms underlying these cardiovascular effects of PM and postulate that cardiovascular dysfunction may be implicated in the effects of PM in other organ systems. The employment of multiple strategies to tackle air pollution, and especially ultrafine particles from vehicles, is likely to be accompanied by improvements in cardiovascular health.
Citations
Cited by
- Environmental risk factors and cardiovascular health
- A comprehensive review/expert statement on environmental risk factors of cardiovascular disease
- National environmental health risk assessment of short-term air pollution effects on cardiovascular disease in Australia: A systematic review and meta-analysis
- Raising Awareness of Authorities by Quantifying Vehicle CO2 Emissions of a Drive-Thru Operation: Insights from a Canadian Case Study
- Oxidative stress and the cardiovascular effects of air pollution. [europepmc]
- Cardiovascular adaptations to particle inhalation exposure: molecular mechanisms of the toxicology. [europepmc]
- Iron-rich air pollution nanoparticles: An unrecognised environmental risk factor for myocardial mitochondrial dysfunction and cardiac oxidative stress. [europepmc]
- Reduction of environmental pollutants for prevention of cardiovascular disease: it's time to act. [europepmc]
- The critical role of endothelial function in fine particulate matter-induced atherosclerosis. [europepmc]
- A Review on Ionic Liquids-Based Membranes for Middle and High Temperature Polymer Electrolyte Membrane Fuel Cells (PEM FCs). [europepmc]
- Heart Failure and PAHs, OHPAHs, and Trace Elements Levels in Human Serum: Results from a Preliminary Pilot Study in Greek Population and the Possible Impact of Air Pollution. [europepmc]
- Air pollution and cardiovascular disease: Can the Australian bushfires and global COVID-19 pandemic of 2020 convince us to change our ways? [europepmc]
- Impact of Acute and Chronic Psychosocial Stress on Vascular Inflammation. [europepmc]
- Mechanisms underlying the health effects of desert sand dust. [europepmc]
- Nuclear Receptors in Myocardial and Cerebral Ischemia-Mechanisms of Action and Therapeutic Strategies. [europepmc]
- The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis. [europepmc]
- Links between chronic exposure to outdoor air pollution and cardiovascular diseases: a review. [europepmc]
- A Review of Road Traffic-Derived Non-Exhaust Particles: Emissions, Physicochemical Characteristics, Health Risks, and Mitigation Measures. [europepmc]
- The Impact of Fine Particulate Matter 2.5 on the Cardiovascular System: A Review of the Invisible Killer. [europepmc]
- Protecting playgrounds: local-scale reduction of airborne particulate matter concentrations through particulate deposition on roadside 'tredges' (green infrastructure). [europepmc]
- Effect of Short- to Long-Term Exposure to Ambient Particulate Matter on Cognitive Function in a Cohort of Middle-Aged and Older Adults: KoGES. [europepmc]
- Breathing Fresh Air in the City: Implementing Avenue Trees as a Sustainable Solution to Reduce Particulate Pollution in Urban Agglomerations. [europepmc]
- Particulate Matter Pollution Remains a Threat for Cardiovascular Health: Findings From the Global Burden of Disease 2019. [europepmc]
- Air pollution, glymphatic impairment, and Alzheimer's disease. [europepmc]
- Air Pollution and Cardiac Diseases: A Review of Experimental Studies. [europepmc]
- Ambient air pollution and adverse birth outcomes: A review of underlying mechanisms. [europepmc]
- The potential of micro- and nanoplastics to exacerbate the health impacts and global burden of non-communicable diseases. [europepmc]
- Environmentally Not So Friendly: Global Warming, Air Pollution, and Wildfires: JACC Focus Seminar, Part 1. [europepmc]
- Clearing the Air to Address Pollution's Cardiovascular Health Crisis. [europepmc]
Related