Modeling and simulation of nuclear architecture reorganization process using a phase field approach

2021/03/12 by Qing Cheng, Pourya Delafrouz, Cheng, Qing +7
Engineering · Materials Science · #Aluminum Alloy Microstructure Properties #FOS: Mathematics #Microstructure and mechanical properties #Numerical Analysis (math.NA) #Solidification and crystal growth phenomena

paper · pdf · doi:10.48550/arxiv.2103.09658

openalex publication_date 2021/03/12 · openalex created_date 2021/03/29 · openalex updated_date 2026/07/28

Abstract

We develop a special phase field/diffusive interface method to model the nuclear architecture reorganization process. In particular, we use a Lagrange multiplier approach in the phase field model to preserve the specific physical and geometrical constraints for the biological events. We develop several efficient and robust linear and weakly nonlinear schemes for this new model. To validate the model and numerical methods, we present ample numerical simulations which in particular reproduce several processes of nuclear architecture reorganization from the experiment literature.

Citations

• Multiple Scalar Auxiliary Variable (MSAV) Approach and its Application to the Phase-Field Vesicle Membrane Model

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