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Multi-contrast MPI channel leakage reduction using a two-step measurement and reconstruction method

2024/04/26 by Nawwas, Lina, Möddel, Martin, Knopp, Tobias
Medicine · #Health #Medicine

paper · doi:10.15480/882.9525

Abstract

Magnetic particle imaging (MPI) is an imaging modality that measures the response of magnetic nanoparticle tracers to alternating magnetic fields. There has recently been exploration into multi-contrast MPI, in which the signal from different tracer materials or environments is separately reconstructed, resulting in multi-channel images that enable temperature or viscosity quantification. In this work, we investigate the channel leakage in multi-contrast MPI reconstruction and we introduce a two-step measurement and reconstruction method to quantify and reduce channel leakage between multi-contrast MPI channels.

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