1992/09/01 by Allan Dawson, A R Gibbs, Allen Gibbs +4 · 2 citations
Medicine · #Amphibole #Asbestos #Incidence (geometry) #Lung cancer #Medical Imaging and Pathology Studies #Medical diagnosis #Medicine #Mesothelioma #Occupational and environmental lung diseases #Pathology #Soft tissue tumor case studies
paper · pdf · doi:10.1002/1097-0142(19920901)70:5<1183::aid-cncr2820700526>3.0.co;2-o
openalex publication_date 1992/09/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27
Nine new cases of mesothelioma clustering in four families are described, and additional information is provided on four previously reported families. All of the members of these families had some exposure to asbestos. Diagnoses were confirmed histologically, and the relevance of the histologic pattern is discussed after the literature review. The lung mineral fiber burden was quantified in patients by transmission electron microscopic examination and energy-dispersive x-ray analysis, and this confirmed significant exposure to amphibole asbestos in all patients. Evidence supporting an increased incidence of mesothelioma in family members is discussed.