2024/10/21 by Sacha Grelet, Grelet, Sacha, Alejandro Martínez Jiménez +5
Biochemistry, Genetics and Molecular Biology · Engineering · #Advanced Fluorescence Microscopy Techniques #FOS: Physical sciences #Medical Physics (physics.med-ph) #Optical Coherence Tomography Applications #Optics (physics.optics)
paper · pdf · doi:10.48550/arxiv.2410.15692
openalex publication_date 2024/10/21 · openalex created_date 2024/11/06 · openalex updated_date 2026/07/30
Akinetic swept-sources are essential for high-speed optical coherence tomography (OCT) imaging. Time-stretched supercontinuum (TSSC) lasers have proven to be efficient for multi-MHz swept-sources. However, lack of low-noise broadband lasers and of large dispersion devices in the water low-absorption band at 1060 nm have limited the biomedical applications of TSSC lasers. In this letter, an approach to tune the wavelength around 1050 nm over 90 nm with low-noise at 10 MHz is presented. This is based on all-normal dispersion (ANDi) supercontinuum dynamics, and employs a long chirped fiber Bragg grating (CFBG) to time-stretch a broadband pulse with a duty cycle of 93 %. Retinal images are demonstrated, with a sensitivity of 84 dB - approaching the shot noise limit. We believe this high-speed low-noise swept-source will greatly promote the development of OCT techniques for biomedical applications.