Long-range correlation in the whole human genome

2004/02/25 by R. Mansilla, Mansilla, R., N. Del Castillo +9
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Adaptation and Self-Organizing Systems (nlin.AO) #FOS: Biological sciences #FOS: Physical sciences #Genomics (q-bio.GN) #nlin.AO #q-bio.GN

paper · pdf · doi:10.48550/arxiv.q-bio/0402043

8 pages, 1 figures

arxiv created 2004/02/25 · arxiv updated 2009/12/01

Abstract

We calculate the mutual information function for each of the 24 chromosomes in the human genome. The same correlation pattern is observed regardless the individual functional features of each chromosome. Moreover, correlations of different scale length are detected depicting a multifractal scenario. This fact suggest a unique mechanism of structural evolution. We propose that such a mechanism could be an expansion-modification dynamical system.

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