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Conditional Deformable Image Registration with Spatially-Variant and Adaptive Regularization

2023/03/19 by Yinsong Wang, Wang, Yinsong, Huaqi Qiu +3
Computer Science · Engineering · #Advanced Neural Network Applications #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Medical Image Segmentation Techniques #Robotics and Sensor-Based Localization #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2303.10700

openalex publication_date 2023/03/19 · openalex created_date 2023/03/22 · openalex updated_date 2026/07/28

Abstract

Deep learning-based image registration approaches have shown competitive performance and run-time advantages compared to conventional image registration methods. However, existing learning-based approaches mostly require to train separate models with respect to different regularization hyperparameters for manual hyperparameter searching and often do not allow spatially-variant regularization. In this work, we propose a learning-based registration approach based on a novel conditional spatially adaptive instance normalization (CSAIN) to address these challenges. The proposed method introduces a spatially-variant regularization and learns its effect of achieving spatially-adaptive regularization by conditioning the registration network on the hyperparameter matrix via CSAIN. This allows varying of spatially adaptive regularization at inference to obtain multiple plausible deformations with a single pre-trained model. Additionally, the proposed method enables automatic hyperparameter optimization to avoid manual hyperparameter searching. Experiments show that our proposed method outperforms the baseline approaches while achieving spatially-variant and adaptive regularization.

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