2014/12/10 by Theresa Stocks, Thomas Hillen, Stocks, Theresa +5
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #Advanced Radiotherapy Techniques #FOS: Biological sciences #Medical Imaging Techniques and Applications #Radiation Therapy and Dosimetry #Tissues and Organs (q-bio.TO) #q-bio.TO
paper · pdf · doi:10.48550/arxiv.1412.3441
22 pages, 4 figures
arxiv created 2014/12/10 · openalex publication_date 2014/12/10 · arxiv updated 2014/12/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The normal tissue complication probability (NTCP) is a measure for the estimated side effects of a given radiation treatment schedule. Here we use a stochastic logistic birth death process to define an organ specific and patient specific NTCP. We emphasise an asymptotic simplification which relates the NTCP to the solution of a logistic differential equation. This framework allows for a direct use of the NTCP model in clinical practice. We formulate, but do not solve, related optimization problems.