Jejunal mucosal abnormalities in patients with recurrent aphthous ulceration.

1976/01/03 by R Ferguson, M K Basu, M. K. Basu +3 · 4 citations
Medicine · #Biopsy #Celiac Disease Research and Management #Coeliac disease #Dermatology #Disease #Eosinophilic Esophagitis #Gastroenterology #Internal medicine #Medicine

paper · pdf · doi:10.1136/bmj.1.6000.11

openalex publication_date 1976/01/03 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Jejunal biopsies in 33 patients with troublesome recurrent aphthous ulceration seen over one year showed eight with flat mucosa compatible with coeliac disease. All remitted completely on a gluten-free diet, both clinically and haematologically, and the aphthous ulceration did not recur. Gluten sensitivity is aetiologically important in patients with recurrent aphthous ulceration and flat mucosa, and patients with recurrent ulceration should undergo jejunal biopsy.

Cited by

• Oral Manifestations of Celiac Disease
• Gluten sensitivity enteropathy in patients with recurrent aphthous stomatitis. [europepmc]
• Urban legends: recurrent aphthous stomatitis. [europepmc]
• Cutaneous and Mucosal Manifestations Associated with Celiac Disease. [europepmc]

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