Gut hormones in tropical malabsorption.

1979/11/17 by H S Besterman, G C Cook, Guillermo Cook +9 · 8 citations
Medicine · Nursing · #Basal (medicine) #Biochemical Analysis and Sensing Techniques #Biology #Endocrinology #Gastrointestinal motility and disorders #Glycogen Storage Diseases and Myoclonus #Hormone #Insulin #Internal medicine #Malabsorption #Malabsorption syndromes #Medicine #Motilin #Pathophysiology #Postprandial

paper · pdf · doi:10.1136/bmj.2.6200.1252

openalex publication_date 1979/11/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Concentrations of various gut hormones were measured after a test breakfast in eight patients with severe tropical malabsorption and 12 controls. The patients with tropical malabsorption had greatly raised basal plasma motilin and enteroglucagon concentrations, but their postprandial release of both gastric inhibitory polypeptide and insulin was significantly reduced. The pattern of gut hormone release differed from that found in coeliac disease. The measurement of gut hormones, each of which has a specific site and function, thus throws new light on the pathophysiology of tropical malabsorption and may suggest approaches of treatment.

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