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Comparative Analysis of Machine Learning and Deep Learning Models for Classifying Squamous Epithelial Cells of the Cervix

2024/11/20 by Subhasish Das, Das, Subhasish, Satish K. Panda +7
Medicine · #Cervical Cancer and HPV Research #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2411.13535

openalex publication_date 2024/11/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

The cervix is the narrow end of the uterus that connects to the vagina in the female reproductive system. Abnormal cell growth in the squamous epithelial lining of the cervix leads to cervical cancer in females. A Pap smear is a diagnostic procedure used to detect cervical cancer by gently collecting cells from the surface of the cervix with a small brush and analyzing their changes under a microscope. For population-based cervical cancer screening, visual inspection with acetic acid is a cost-effective method with high sensitivity. However, Pap smears are also suitable for mass screening due to their higher specificity. The current Pap smear analysis method is manual, time-consuming, labor-intensive, and prone to human error. Therefore, an artificial intelligence (AI)-based approach for automatic cell classification is needed. In this study, we aimed to classify cells in Pap smear images into five categories: superficial-intermediate, parabasal, koilocytes, dyskeratotic, and metaplastic. Various machine learning (ML) algorithms, including Gradient Boosting, Random Forest, Support Vector Machine, and k-Nearest Neighbor, as well as deep learning (DL) approaches like ResNet-50, were employed for this classification task. The ML models demonstrated high classification accuracy; however, ResNet-50 outperformed the others, achieving a classification accuracy of 93.06%. This study highlights the efficiency of DL models for cell-level classification and their potential to aid in the early diagnosis of cervical cancer from Pap smear images.

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