YHap: software for probabilistic assignment of Y haplogroups from population re-sequencing data

2013/04/11 by Fan Zhang, Ruoyan Chen, Zhang, Fan +15
Biochemistry, Genetics and Molecular Biology · #Evolution and Genetic Dynamics #FOS: Biological sciences #Forensic and Genetic Research #Genetic diversity and population structure #Genomics (q-bio.GN) #Populations and Evolution (q-bio.PE)

paper · pdf · doi:10.48550/arxiv.1304.3351

openalex publication_date 2013/04/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Y haplogroup analyses are an important component of genealogical reconstruction, population genetic analyses, medical genetics and forensics. These fields are increasingly moving towards use of low-coverage, high throughput sequencing. However, there is as yet no software available for using sequence data to assign Y haplogroup groups probabilistically, such that the posterior probability of assignment fully reflects the information present in the data, and borrows information across all samples sequenced from a population. YHap addresses this problem.

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