Functional remediation in bipolar disorder: 1-year follow-up of neurocognitive and functional outcome

2015/11/06 by Caterina del Mar Bonnín, C. M. Bonnin, Carla Torrent +28 · 22 citations
Medicine · #Bipolar Disorder and Treatment #Schizophrenia research and treatment #Treatment of Major Depression

paper · pdf · doi:10.1192/bjp.bp.114.162123

Abstract

BACKGROUND: Few randomised clinical trials have examined the efficacy of an intervention aimed at improving psychosocial functioning in bipolar disorder. AIMS: To examine changes in psychosocial functioning in a group that has been enrolled in a functional remediation programme 1 year after baseline. METHOD: This was a multicentre, randomised, rater-masked clinical trial comparing three patient groups: functional remediation, psychoeducation and treatment as usual over 1-year follow-up. The primary outcome was change in psychosocial functioning measured by means of the Functioning Assessment Short Test (FAST). Group×time effects for overall psychosocial functioning were examined using repeated-measures ANOVA (trial registration NCT01370668). RESULTS: There was a significant group×time interaction for overall psychosocial functioning, favouring patients in the functional remediation group (F = 3.071, d.f. = 2, P = 0.049). CONCLUSIONS: Improvement in psychosocial functioning is maintained after 1-year follow-up in patients with bipolar disorder receiving functional remediation.

Citations

• Efficacy of Functional Remediation in Bipolar Disorder: A Multicenter Randomized Controlled Study

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