First Case of 2019 Novel Coronavirus in the United States
2020/01/31 by Michelle Holshue, Chas DeBolt, Scott Lindquist +21 · 1 voice · 6,403 citations
Medicine · #2019-20 coronavirus outbreak #COVID-19 Clinical Research Studies #COVID-19 and healthcare impacts #China #Coronavirus #Coronavirus disease 2019 (COVID-19) #Disease #Environmental health #Family medicine #Infectious disease (medical specialty) #Intensive care medicine #Internal medicine #Medicine #Outbreak #Pathology #Pneumonia #Political science #Presentation (obstetrics) #Public health #SARS-CoV-2 and COVID-19 Research #Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) #Surgery #Virology
paper · open access · doi:10.1056/nejmoa2001191
published in New England Journal of Medicine 382(10), 929-936 (Massachusetts Medical Society)
openalex publication_date 2020/01/31 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04
Abstract
An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.
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