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Rigorous results for a population model with selection I: evolution of the fitness distribution

2015/07/01 by Jason Schweinsberg, Schweinsberg, Jason · 2 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · Medicine · Social Sciences · #Evolution and Genetic Dynamics #Evolutionary Game Theory and Cooperation #Mathematical and Theoretical Epidemiology and Ecology Models #math.PR #msc:60J27 #msc:60J75 #msc:60J80 #msc:92D15 #msc:92D25

paper · pdf · doi:10.48550/arxiv.1507.00393

99 pages

arxiv created 2015/07/01 · arxiv updated 2015/07/03

Abstract

We consider a model of a population of fixed size N undergoing selection. Each individual acquires beneficial mutations at rate μN, and each beneficial mutation increases the individual's fitness by sN. Each individual dies at rate one, and when a death occurs, an individual is chosen with probability proportional to the individual's fitness to give birth. Under certain conditions on the parameters μN and sN, we obtain rigorous results for the rate at which mutations accumulate in the population and the distribution of the fitnesses of individuals in the population at a given time. Our results confirm predictions of Desai and Fisher (2007).

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