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Abnormality Detection and Localization in Chest X-Rays using Deep Convolutional Neural Networks

2017/05/27 by Mohammad Tariqul Islam, Md Abdul Aowal, Islam, Mohammad Tariqul +5 · 8 citations
Computer Science · Medicine · #AI in cancer detection #COVID-19 diagnosis using AI #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #Lung Cancer Diagnosis and Treatment #Radiomics and Machine Learning in Medical Imaging #cs.CV

paper · pdf · doi:10.48550/arxiv.1705.09850

14 figures, 16 pages, 8 tables

openalex publication_date 2017/05/27 · arxiv created 2017/09/27 · arxiv updated 2017/09/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Chest X-Rays (CXRs) are widely used for diagnosing abnormalities in the heart and lung area. Automatically detecting these abnormalities with high accuracy could greatly enhance real world diagnosis processes. Lack of standard publicly available dataset and benchmark studies, however, makes it difficult to compare various detection methods. In order to overcome these difficulties, we have used a publicly available Indiana CXR, JSRT and Shenzhen dataset and studied the performance of known deep convolutional network (DCN) architectures on different abnormalities. We find that the same DCN architecture doesn't perform well across all abnormalities. Shallow features or earlier layers consistently provide higher detection accuracy compared to deep features. We have also found ensemble models to improve classification significantly compared to single model. Combining these insight, we report the highest accuracy on chest X-Ray abnormality detection on these datasets. We find that for cardiomegaly detection, the deep learning method improves the accuracy by a staggering 17 percentage point compared to rule based methods. We applied the techniques to the problem of tuberculosis detection on a different dataset and achieved the highest accuracy. Our localization experiments using these trained classifiers show that for spatially spread out abnormalities like cardiomegaly and pulmonary edema, the network can localize the abnormalities successfully most of the time. One remarkable result of the cardiomegaly localization is that the heart and its surrounding region is most responsible for cardiomegaly detection, in contrast to the rule based models where the ratio of heart and lung area is used as the measure. We believe that through deep learning based classification and localization, we will discover many more interesting features in medical image diagnosis that are not considered traditionally.

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