Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage

2014/02/03 by Lei Lü, Lei Lu, Arnavaz Hajizadeh Barfejani +4 · 25 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Intracerebral and Subarachnoid Hemorrhage Research #Sphingolipid Metabolism and Signaling #Spinal Hematomas and Complications

paper · doi:10.1016/j.brainres.2014.01.048

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• Fingolimod confers neuroprotection through activation of Rac1 after experimental germinal matrix hemorrhage in rat pups. [europepmc]
• Modulators of microglial activation and polarization after intracerebral haemorrhage. [europepmc]
• Programmed Cell Death after Intracerebral Hemorrhage. [europepmc]
• Preclinical Studies and Translational Applications of Intracerebral Hemorrhage. [europepmc]
• Research Progress in Understanding the Relationship Between Heme Oxygenase-1 and Intracerebral Hemorrhage. [europepmc]
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• Emerging Pharmacological Treatments for Cerebral Edema: Evidence from Clinical Studies. [europepmc]
• Neuroinflammation after Intracerebral Hemorrhage and Potential Therapeutic Targets. [europepmc]
• From the Molecular Mechanism to Pre-clinical Results: Anti-epileptic Effects of Fingolimod. [europepmc]
• Perihematomal Edema and Clinical Outcome in Intracerebral Hemorrhage Related to Different Oral Anticoagulants. [europepmc]
• Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage. [europepmc]
• Microglia Phenotype and Intracerebral Hemorrhage: A Balance of Yin and Yang. [europepmc]
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• Selective sphingosine-1-phosphate receptor 1 modulator attenuates blood-brain barrier disruption following traumatic brain injury by inhibiting vesicular transcytosis. [europepmc]
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• Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage. [europepmc]
• Clinical Potential of Immunotherapies in Subarachnoid Hemorrhage Treatment: Mechanistic Dissection of Innate and Adaptive Immune Responses. [europepmc]