2024/03/12 by Cao, Thanh-Luu, Oh, Seungjun, Le, Tuan-Anh +4
#Magnetic Hyperthermia #amplitude modulation #human MPI #temperature imaging
paper · doi:10.18416/ijmpi.2024.2403039
Magnetic Particle Imaging (MPI) is an emerging non-invasive medical imaging method capable of determining the concentration and spatial distribution of superparamagnetic iron oxide (SPIO) nanoparticles. Ongoing research is exploring technology to estimate the temperature of particles based on MPI signals. In magnetic hyperthermia treatment, volumetric temperature measurement is crucial for ensuring the safety of healthy tissues. While the efficacy of magnetic hyperthermia and simulation-based methods for estimating temperature and damage is now recognized, no prior studies have reported a human-sized MPI system that integrates hyperthermia and MPI. Such integration could potentially allow for non-invasive treatments. In this paper, we present the design and manufacture of a theranostic platform with the potential for MPI, magnetic hyperthermia and thermometry. The development of such technology could greatly extend the application of MPI in planning magnetic hyperthermia treatments.