Computation of writhe in modeling of supercoiled DNA

2000/01/01 by Konstantin Klenin, Konstantin V. Klenin, Jörg Langowski · 30 citations
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · Engineering · #DNA and Nucleic Acid Chemistry #Force Microscopy Techniques and Applications #Nanofabrication and Lithography Techniques

paper · doi:10.1002/1097-0282(20001015)54:5<307::aid-bip20>3.0.co;2-y

Abstract

We describe four previously unpublished methods allowing the computation of the writhe for a supercoiled DNA molecule modeled by a polymer chain consisting of straight segments. These methods are compared with each other in terms of computational efficiency and the scope of their applicability is discussed.

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