Photophysics of Clomeleon by FLIM: Discriminating Excited State Reactions along Neuronal Development

2006/12/15 by Mini Jose, Deepak Nair, Deepak K. Nair +4 · 11 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Neuroscience · #Acceptor #Advanced Fluorescence Microscopy Techniques #Atomic physics #Biophysics #Chemical physics #Chemistry #Electron transfer #Energy transfer #Excited state #Fluorescence #Fluorescence-lifetime imaging microscopy #Förster resonance energy transfer #Kinetics #Microscopy #Optics #Photochemistry #Photoinduced electron transfer #Photoreceptor and optogenetics research #Quenching (fluorescence) #Spectroscopy #bioluminescence and chemiluminescence research

paper · pdf · doi:10.1529/biophysj.106.092841

openalex publication_date 2006/12/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/19

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• Image-Based Marker-Free Screening of GABAA Agonists, Antagonists, and Modulators
• Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. [europepmc]
• Quantitative imaging for discovery and assembly of the metabo-regulome. [europepmc]
• Genetically encoded optical sensors for monitoring of intracellular chloride and chloride-selective channel activity. [europepmc]
• Phase differential enhancement of FLIM to distinguish FRET components of a biosensor for monitoring molecular activity of Membrane Type 1 Matrix Metalloproteinase in live cells. [europepmc]
• Advanced fluorescence microscopy techniques--FRAP, FLIP, FLAP, FRET and FLIM. [europepmc]
• Twenty years of fluorescence imaging of intracellular chloride. [europepmc]
• Application of fluorescence resonance energy transfer in protein studies. [europepmc]
• Image-Based Marker-Free Screening of GABA A Agonists, Antagonists, and Modulators. [europepmc]
• Live Cell Imaging of ATP Levels Reveals Metabolic Compartmentalization within Motoneurons and Early Metabolic Changes in FUS ALS Motoneurons. [europepmc]
• Chloride Homeostasis in Neuronal Disorders: Bridging Measurement to Therapy. [europepmc]