A model for association in bivariate life tables and its application in epidemiological studies of familial tendency in chronic disease incidence

1978/01/01 by D. G. CLAYTON, David Clayton · 2,060 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · Medicine · Social Sciences · #Advanced Causal Inference Techniques #Bivariate analysis #Clinical epidemiology #Demography #Disease #Epidemiology #Genetic Associations and Epidemiology #Gerontology #Health disparities and outcomes #Incidence (geometry) #Mathematics #Medicine #Pathology #Sociology #Statistics

paper · doi:10.1093/biomet/65.1.141

published in Biometrika 65(1), 141-151 (Oxford University Press)

openalex publication_date 1978/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04

Abstract

The application of Cox's (1972) regression model for censored survival data to epidemio-logical studies of chronic disease incidence is discussed. A related model for association in bivariate survivorship time distributions is proposed for the analysis of familial tendency in disease incidence. The possible extension of the model to general multivariate survivorship distributions is indicated.

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