2025/04/14 by Pawel Szczypkowski, Adrian Makowski, Szczypkowski, Pawel +12
Physics and Astronomy · #Biological Physics (physics.bio-ph) #FOS: Physical sciences #Materials Science (cond-mat.mtrl-sci) #Medical Physics (physics.med-ph) #Optics (physics.optics) #cond-mat.mtrl-sci #physics.bio-ph #physics.med-ph #physics.optics
paper · pdf · doi:10.48550/arxiv.2504.10423
All the comments welcome - check the newest version (v4)
arxiv created 2026/07/29 · arxiv updated 2026/07/30
While scattered light conveys most of the information we perceive, scattering may also distort that information before it reaches our detectors. The problem is acute in many applications, such as in high-resolution microscopy of biological tissue, where scattering degrades both resolution and signal-to-noise ratio. Here, for the first time, we demonstrate that combining two intrinsic properties of scattered light: speckle statistics and the memory effect, with highly non-linear optical response yields, rather surprisingly, super-resolution, low-background, non-invasive imaging of objects completely hidden behind a strongly scattering, opaque layers. Crucially, our technique of Nonlinear Imaging with Speckle Excitation (NISE) does not resort to wavefront shaping, adaptive optics, complicated optical setups, or iterative image reconstruction algorithms. Because the strategy relies solely on the properties of scattered light and high-order nonlinear response of the luminescent labels, it can be applied to any speckle-forming propagation, from biological tissue to multicore fibers, combined with any type of phenomenon that exhibits a sufficiently high order nonlinearity.