2024/08/12 by Marco Riccardi, Olivier J. F. Martin, Riccardi, Marco +1
Biochemistry, Genetics and Molecular Biology · Engineering · Medicine · #Applied Physics (physics.app-ph) #Biofield Effects and Biophysics #Chemical Physics (physics.chem-ph) #FOS: Physical sciences #Fractal and DNA sequence analysis #Mesoscale and Nanoscale Physics (cond-mat.mes-hall) #Molecular Communication and Nanonetworks #Optics (physics.optics)
paper · pdf · doi:10.48550/arxiv.2408.06151
openalex publication_date 2024/08/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The manipulation of nanoscale matter has the potential to revolutionize a variety of fields across nanoscience and technology. Here, we demonstrate experimentally and characterize numerically a device that combines the benefits of dielectrophoresis (DEP) - long-range and strong trapping forces - with those of plasmonic tweezers - high sensitivities - to achieve a remarkable efficiency in the trapping and sensing of metallic nanoparticles and biomolecules. In particular, we show the DEP trapping and surface enhanced Raman scattering characterization of bovine serum albumin and Rhodamine B, thus extending the applications of tweezing devices to molecules having masses of only a few hundreds of Da. This range covers virtually any molecule relevant for life, from tiny oligopeptides to large proteins. This pushes our manipulation capabilities deep into the realms of efficient single-molecule biosensing and quantum science, providing a powerful platform to probe matter at the nanoscale.