Rare Copy Number Variants Are Associated With Poorer Cognition in Schizophrenia

2020/12/18 by Leon Hubbard, Elliott Rees, Derek W. Morris +21 · 12 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Genomic variations and chromosomal abnormalities #Schizophrenia research and treatment #Genetic Associations and Epidemiology

paper · doi:10.1016/j.biopsych.2020.11.025

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• Genome-wide study of copy number variation implicates multiple novel loci for schizophrenia risk in Han Chinese family trios. [europepmc]
• Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice. [europepmc]
• Ultrarare Coding Variants and Cognitive Function in Schizophrenia. [europepmc]
• Similar Rates of Deleterious Copy Number Variants in Early-Onset Psychosis and Autism Spectrum Disorder. [europepmc]
• Schizophrenia: A Narrative Review of Etiopathogenetic, Diagnostic and Treatment Aspects. [europepmc]
• Cognitive impairment in psychiatric diseases: Biomarkers of diagnosis, treatment, and prevention. [europepmc]
• Family-based analysis of the contribution of rare and common genetic variants to school performance in schizophrenia. [europepmc]
• A review of the cognitive impact of neurodevelopmental and neuropsychiatric associated copy number variants. [europepmc]
• Copy Number Variations in Neuropsychiatric Disorders. [europepmc]
• Differences of regional homogeneity and cognitive function between psychotic depression and drug-naïve schizophrenia. [europepmc]
• Effect of polygenic scores on the relationship between psychosis and cognition. [europepmc]
• Genetics to Improve Outcomes in Schizophrenia (GENios): A within-case molecular genetic study protocol. [europepmc]