Genetics in conservation management: Revised recommendations for the 50/500 rules, Red List criteria and population viability analyses
2014/01/25 by Richard Frankham, Corey J. A. Bradshaw, Corey J.A. Bradshaw +1 · 1 voice · 1,180 citations
Biochemistry, Genetics and Molecular Biology · Environmental Science · #Biology #Conservation genetics #Demography #Ecology #Effective population size #Endangered species #Genetic and phenotypic traits in livestock #Genetic diversity #Genetic diversity and population structure #Genetics #IUCN Red List #Inbreeding #Inbreeding depression #Minimum viable population #Population #Population size #Population viability analysis #Small population size #Species Distribution and Climate Change #Threatened species
paper · open access · doi:10.1016/j.biocon.2013.12.036
published in Biological Conservation 170, 56-63 (Elsevier BV)
openalex publication_date 2014/01/25 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
Citations
Cited by
- Threatened plant translocation in Australia: A review
- The application gap: Genomics for biodiversity and ecosystem service management
- Using Historic and Contemporary Genomes to Assess the Genetic Consequences of a Population Decline in an Endangered Tern Population
- Global extinction risk for seahorses, pipefishes and their near relatives (Syngnathiformes)
- Applications of Primate Genetics for Conservation and Management
- Building quantitative resources using PVA to assess the responses of UK seabirds to extrinsic threats
- Evidence of genetic structure in the wide-ranging bearded vulture (Gypaetus barbatus (Linnaeus, 1758))
- Genomic erosion across avian lineages in the context of their evolutionary history
- Phylogeography, genetic diversity, and population structure of Nile crocodile populations at the fringes of the southern African distribution
- Genomic evidence for a hybrid origin of the critically endangered shrub Callistemon kenmorrisonii (Myrtaceae) and persistence involving extreme clonality
- The different fates of two Asian horseshoe crab species with different dispersal abilities
- High inter-population connectivity and occasional gene flow between subspecies improves recovery potential for the endangered Least Bell’s Vireo
- Nucleotide diversity is a poor predictor of short-term adaptive potential
- Dynamics of neutral genes and genes under selection and their implications for threatened species translocations
- Recent Demographic History Inferred From Allele Frequency Spectra: Evaluation by Simulations and Insights From Pool Sequencing of Wild Bees
- Predicting success of conservation translocations: prerelease screening tools for a threatened marsupial
- A Shift to Metapopulation Genetic Management for Persistence of a Species Threatened by Fragmentation: The Case of an Endangered Australian Freshwater Fish
- Simulating Genetic Mixing in Strongly Structured Populations of the Threatened Southern Brown Bandicoot (Isoodon obesulus)
- Estimating the Effective Population Size Across Space and Time in the Critically Endangered Western Chimpanzee in Guinea‐Bissau: Challenges and Implications for Conservation Management
- Expanding from local to continental scale—A genetic assessment of the Eurasian wolverine
- Evaluating inbreeding and assessing the risk of outbreeding depression in genetic rescue using whole-genome sequence data
- Seven reasons why threatened species managers must consider genetic health
- Population genetics, demography and conservation of Mediterranean brown trout from Sardinia
- Genetic diversity targets and indicators in the CBD post-2020 Global Biodiversity Framework must be improved
- Sibship and parentage reconstruction as genetic tool for designing and monitoring plant translocations
- Genomic Diversity as a Key Conservation Criterion: Proof‐of‐Concept From Mammalian Whole‐Genome Resequencing Data
- Limits to species’ range: the tension between local and global adaptation
- Whole‐Genome Evaluation of Genetic Rescue: The Case of a Curiously Isolated and Endangered Butterfly
- Gene flow prevents genetic diversity loss despite small effective population size in fragmented grizzly bear (Ursus arctos) populations
- Conservation genomics of Pecos pupfish ( Cyprinodon pecosensis )
- Genome-wide SNP data reveal hidden hierarchical population structure and demographic history of endangered black-and-white snub-nosed monkeys ( Rhinopithecus bieti )
- Current state of plant conservation translocations across Europe: motivations, challenges and outcomes
- Museum genomics suggests long-term population decline in a putatively extinct bumble bee
- Long-Term Noninvasive Genetic Monitoring Guides Recovery of the Endangered Columbia Basin Pygmy Rabbits (Brachylagus idahoensis)
- Purging of Highly Deleterious Mutations Through an Extreme Bottleneck
- Balancing Inbreeding and Outbreeding Risks to Inform Translocations Throughout the Range of an Imperiled Darter
- Rapid establishment of species barriers in plants compared with that in animals
- A Dominant Founder Lineage Has Possible Fitness Costs for the Endangered Mexican Grey Wolf
- Genetic rescue of small inbred populations: meta‐analysis reveals large and consistent benefits of gene flow
- Genomics and the challenging translation into conservation practice
- Genomic Insights Into Population Structure and Demographic History of White Anglerfish ( Lophius piscatorius ) Throughout Its Range
- Estimating current effective sizes of large populations from a single sample of genomic marker data: A comparison of estimators by simulations
- Stochastic population models to identify optimal and cost‐effective harvest strategies for feral pig eradication
- Dealing With the Complexity of Effective Population Size in Conservation Practice
- Stochastic models support rapid peopling of Late Pleistocene Sahul
- Relative demographic susceptibility does not explain the extinction chronology of Sahul’s megafauna
- Alternativas a la harina de pescado en dietas para lechones post-destete
- Minimum founding populations for the first peopling of Sahul
- Opportunities to improve the future of South Australia’s terrestrial biodiversity
- Small populations of Palaeolithic humans in Cyprus hunted endemic megafauna to extinction
- Demographic models predict end-Pleistocene arrival and rapid expansion of pre-agropastoralist humans in Cyprus
- Applying genomic approaches to identify historic population declines in European forest bats
- 50/500 or 100/1000 debate is not about the time frame - Reply to Rosenfeld
- Life on the edge: Mesolithic population size and viability on Malta
- Circling the drain: the extinction crisis and the future of humanity
- When roads appear jaguars decline: Increased access to an Amazonian wilderness area reduces potential for jaguar conservation
- Extinctions in near time: new radiocarbon dates point to a very recent disappearance of the South American foxDusicyon avus(Carnivora: Canidae)
- Turnover and post‐bottleneck genetic structure in a recovering population of Peregrine Falcons Falco peregrinus
- Lemurs in a dying forest: Factors influencing lemur diversity and distribution in forest remnants of north-eastern Madagascar
- Genetic diversity and differentiation of the Critically Endangered Hispaniolan palm Coccothrinax jimenezii M.M. Mejía & R.G. García based on novel SSR markers
- What can livestock breeders learn from conservation genetics and vice versa? [europepmc]
- Genetic and demographic recovery of an isolated population of brown bear Ursus arctos L., 1758. [europepmc]
- Interactions between demography, genetics, and landscape connectivity increase extinction probability for a small population of large carnivores in a major metropolitan area. [europepmc]
- Artificial barriers prevent genetic recovery of small isolated populations of a low-mobility freshwater fish. [europepmc]
- Next-generation metrics for monitoring genetic erosion within populations of conservation concern. [europepmc]
- Genetic and genomic monitoring with minimally invasive sampling methods. [europepmc]
- Global genomic diversity and conservation priorities for domestic animals are associated with the economies of their regions of origin. [europepmc]
- Co-extinctions annihilate planetary life during extreme environmental change. [europepmc]
- Genetic diversity in fishes is influenced by habitat type and life-history variation. [europepmc]
- Complex problems need detailed solutions: Harnessing multiple data types to inform genetic management in the wild. [europepmc]
- Low genetic diversity and shallow population structure in the endangered vulture, Gyps coprotheres. [europepmc]
- Genetic signatures of small effective population sizes and demographic declines in an endangered rattlesnake, Sistrurus catenatus . [europepmc]
- Early human settlement of Sahul was not an accident. [europepmc]
- Genomic analyses suggest adaptive differentiation of northern European native cattle breeds. [europepmc]
- Chronic radiation exposure at Chernobyl shows no effect on genetic diversity in the freshwater crustacean, Asellus aquaticus thirty years on. [europepmc]
- Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex. [europepmc]
- The Seagrass Methylome Is Associated With Variation in Photosynthetic Performance Among Clonal Shoots. [europepmc]
- Patterns of Genetic Diversity and Mating Systems in a Mass-Reared Black Soldier Fly Colony. [europepmc]
- One Conservation: the integrated view of biodiversity conservation. [europepmc]
- Extensive standing genetic variation from a small number of founders enables rapid adaptation in Daphnia. [europepmc]
- Genomic Data Reveals Population Genetic and Demographic History of Magnolia fistulosa (Magnoliaceae), a Plant Species With Extremely Small Populations in Yunnan Province, China. [europepmc]
- Circling the drain: the extinction crisis and the future of humanity. [europepmc]
- Challenges in quantifying genome erosion for conservation. [europepmc]
- Genetic diversity goals and targets have improved, but remain insufficient for clear implementation of the post-2020 global biodiversity framework. [europepmc]
- Genetic diversity, population genetic structure and gene flow in the rare and endangered wild plant Cypripedium macranthos revealed by genotyping-by-sequencing. [europepmc]
Discussions