2022/09/07 by Jing Ouyang, Ouyang, Jing, Kean Ming Tan +3 · 2 citations
Mathematics · #Advanced Causal Inference Techniques #FOS: Computer and information sciences #Methodology (stat.ME) #Statistical Methods and Bayesian Inference #Statistical Methods and Inference
paper · pdf · doi:10.48550/arxiv.2209.03482
openalex publication_date 2022/09/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Statistical inferences for high-dimensional regression models have been extensively studied for their wide applications ranging from genomics, neuroscience, to economics. However, in practice, there are often potential unmeasured confounders associated with both the response and covariates, which can lead to invalidity of standard debiasing methods. This paper focuses on a generalized linear regression framework with hidden confounding and proposes a debiasing approach to address this high-dimensional problem, by adjusting for the effects induced by the unmeasured confounders. We establish consistency and asymptotic normality for the proposed debiased estimator. The finite sample performance of the proposed method is demonstrated through extensive numerical studies and an application to a genetic data set.