Glycoprotein nonmetastatic B as a pharmacological target in cancer: structural mechanisms, druggability, and therapeutic translation

2026/07/01 by Haixia Wang, Ruiming Wen, Zhongwei Yang +1
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Glycosylation and Glycoproteins Research #Toxin Mechanisms and Immunotoxins #Monoclonal and Polyclonal Antibodies Research

paper · doi:10.1016/j.bcp.2026.118289

Citations

• Affinity‐matured anti‐glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas
• nmb, a novel gene, is expressed in low‐metastatic human melanoma cell lines and xenografts
• FTO/m6A/GPNMB axis: a novel promising target for hepatocellular carcinoma (HCC) treatment?