Myosin phosphatase target subunit: Many roles in cell function

2008/01/07 by Fumio Matsumura, David J. Hartshorne · 26 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Muscle Physiology and Disorders #Cardiomyopathy and Myosin Studies #Cellular Mechanics and Interactions

paper · doi:10.1016/j.bbrc.2007.12.090

Citations

• Myosin phosphatase isoform switching in vascular smooth muscle development

Cited by

• Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1
• Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1. [europepmc]
• Rho-regulated myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation. [europepmc]
• Non-muscle myosin II takes centre stage in cell adhesion and migration. [europepmc]
• RhoA/Rho-kinase: pathophysiologic and therapeutic implications in gastrointestinal smooth muscle tone and relaxation. [europepmc]
• Structural signature of the MYPT1-PP1 interaction. [europepmc]
• LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. [europepmc]
• The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier? [europepmc]
• Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse. [europepmc]
• Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells. [europepmc]
• Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis. [europepmc]
• LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression. [europepmc]
• Drosophila PATJ supports adherens junction stability by modulating Myosin light chain activity. [europepmc]
• Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1. [europepmc]
• MYPT1 regulates contractility and microtubule acetylation to modulate integrin adhesions and matrix assembly. [europepmc]
• STRIPAK components determine mode of cancer cell migration and metastasis. [europepmc]
• Myosin II isoform co-assembly and differential regulation in mammalian systems. [europepmc]
• Signalling scaffolds and local organization of cellular behaviour. [europepmc]
• Calcium Sensitization Mechanisms in Gastrointestinal Smooth Muscles. [europepmc]
• Autophagy and the Cell Cycle: A Complex Landscape. [europepmc]
• Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility. [europepmc]
• PGC-1a integrates a metabolism and growth network linked to caloric restriction. [europepmc]
• Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription. [europepmc]
• The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction. [europepmc]
• Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis. [europepmc]
• SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming. [europepmc]