N-Acetylglutamate and N-acetylmethionine compromise mitochondrial bioenergetics homeostasis and glutamate oxidation in brain of developing rats: Potential implications for the pathogenesis of ACY1 deficiency

2023/10/17 by Vanessa Trindade Bortoluzzi, Rafael Teixeira Ribeiro, Camila Vieira Pinheiro +9 · 5 citations
Biochemistry, Genetics and Molecular Biology · #ATP Synthase and ATPases Research #Biochemistry #Bioenergetics #Biology #Citrate synthase #Citric acid cycle #Enzyme #Genetics and Neurodevelopmental Disorders #Glutamate dehydrogenase #Glutamate receptor #Isocitrate dehydrogenase #Malate dehydrogenase #Mitochondrial Function and Pathology #Mitochondrial respiratory chain #Mitochondrion #Oxidative phosphorylation #Receptor #Respiratory chain #Succinate dehydrogenase

paper · doi:10.1016/j.bbrc.2023.149123

published in Biochemical and Biophysical Research Communications 684, 149123 (Elsevier BV)

openalex publication_date 2023/10/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Citations

• Biochemical and molecular investigations in respiratory chain deficiencies
• Differential investigation of the capacity of succinate oxidation in human skeletal muscle
• Mutations in ACY1, the Gene Encoding Aminoacylase 1, Cause a Novel Inborn Error of Metabolism

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