2025/04/01 by Egbebi, A. H., Ofotoku, D. E., Ogunyemi, O. M. +5
#Ado-Ekiti #Antibiogram #UTI #Uropathogens #students
paper · doi:10.71637/tnhj.v25i1.951
Background: Urinary tract infections (UTIs) are a major public health concern, particularly in underdeveloped nations. It is one of the most prevalent infections in human, with patterns of antibiotic resistance and the distribution of etiological agents changing periodically and regionally. This sought to determine the frequency and profiles of antibiotic-resistant microorganisms among student at Afe Babalola University in Ado-Ekiti, Ekiti State, Nigeria, who appeared to be in good health, in order to discover uropathogens. Methods: Ninety (90) clean-catch midstream early morning urine specimens were collected, cultured and the isolated organisms were identified using con95ventional microbiological techniques within two hours of collection. Results: Twenty (22.2%) of the 90 urine specimens that were examined were positive for uropathogens. The most often isolated species were S. aureus, with 15 (16.67%), K. pneumonia, with 3 (3.33%), and P. aeruginosa, P. mirabilis, with 1 (1.11) each. It was shown that women experienced UTIs more frequently than men did, with 28 (20%) against 2 (2.22%). Gram-positive organisms were highly resistant to streptomycin, but Gram-negative organisms were very resistant to levofloxacin. The most effective medications were imipenem, cefexime, ceftriaxone, and nalidixic acid for Gram-negative organisms and ampicillin, roxithromycin, cloxacillin, tetracycline, and co-trimoxazole for Gram positive isolate. Conclusion: There is a high level of antibiotic resistance among uropathogens in our environment. As a result, better antibiotic management and ongoing surveillance are required.