Measurement of minute volumes of chiral molecules using in-fiber polarimetry

2022/08/29 by Schorn, Florian, Essert, Arabella, Zhong, Yu +4
#FOS: Physical sciences #Optics (physics.optics)

paper · doi:10.48550/arxiv.2208.13457

Abstract

We report an opto-fluidic method that enables to efficiently measure the enantiomeric excess of chiral molecules at low concentration. The approach is to monitor the optical activity induced by a Kagome-lattice hollow-core photonic crystal fiber filled with a sub-ul volume of chiral compound. The technique also allows monitoring the enzymatic racemization of R mandelic acid.

Related

• Continuous-Wave Cavity Ring-Down for High-Sensitivity Polarimetry and Magnetometry Measurements
• Observation of Rayleigh Optical Activity for Chiral Molecules: A New Chiroptical Tool
• Tilting light's polarization plane to spatially separate the nonlinear optical response of chiral molecules on ultrafast timescales
• Ultrafast optical rotation for extremely sensitive\n enantio-discrimination
• Structuring the local handedness of synthetic chiral light: global chirality versus polarization of chirality