2020/10/08 by Joonas A. Autio, Autio, Joonas A., Qi Zhu +23
Medicine · #Advanced MRI Techniques and Applications #FOS: Biological sciences #Glioma Diagnosis and Treatment #Medical Imaging Techniques and Applications #Neurons and Cognition (q-bio.NC)
paper · pdf · doi:10.48550/arxiv.2010.04325
openalex publication_date 2020/10/08 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Recent methodological advances in MRI have enabled substantial growth in\nneuroimaging studies of non-human primates (NHPs), while open data-sharing\nthrough the PRIME-DE initiative has increased the availability of NHP MRI data\nand the need for robust multi-subject multi-center analyses. Streamlined\nacquisition and analysis protocols would accelerate and improve these efforts.\nHowever, consensus on minimal standards for data acquisition protocols and\nanalysis pipelines for NHP imaging remains to be established, particularly for\nmulti-center studies. Here, we draw parallels between NHP and human\nneuroimaging and provide minimal guidelines for harmonizing and standardizing\ndata acquisition. We advocate robust translation of widely used open-access\ntoolkits that are well established for analyzing human data. We also encourage\nthe use of validated, automated pre-processing tools for analyzing NHP data\nsets. These guidelines aim to refine methodological and analytical strategies\nfor small and large-scale NHP neuroimaging data. This will improve\nreproducibility of results, and accelerate the convergence between NHP and\nhuman neuroimaging strategies which will ultimately benefit fundamental and\ntranslational brain science.\n