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Applied Category Theory for Genomics -- An Initiative

2020/09/06 by Yanying Wu, Wu, Yanying
Biochemistry, Genetics and Molecular Biology · Mathematics · #Category Theory (math.CT) #FOS: Biological sciences #FOS: Mathematics #Genomics (q-bio.GN) #math.CT #q-bio.GN

paper · pdf · doi:10.48550/arxiv.2009.02822

26 pages, 6 figures

arxiv created 2020/09/06 · arxiv updated 2020/09/08

Abstract

The ultimate secret of all lives on earth is hidden in their genomes -- a totality of DNA sequences. We currently know the whole genome sequence of many organisms, while our understanding of the genome architecture on a systematic level remains rudimentary. Applied category theory opens a promising way to integrate the humongous amount of heterogeneous informations in genomics, to advance our knowledge regarding genome organization, and to provide us with a deep and holistic view of our own genomes. In this work we explain why applied category theory carries such a hope, and we move on to show how it could actually do so, albeit in baby steps. The manuscript intends to be readable to both mathematicians and biologists, therefore no prior knowledge is required from either side.

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