Mitochondrial DNA metabolism in early development of zebrafish (Danio rerio)

2012/03/23 by Lucia Artuso, Alessandro Romano, Tiziano Verri +5 · 27 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Mitochondrial Function and Pathology #Birth, Development, and Health #Metabolism and Genetic Disorders

paper · doi:10.1016/j.bbabio.2012.03.019

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• Increase in ER-mitochondria contacts and mitochondrial fusion are hallmarks of mitochondrial activation during embryogenesis
• Mutation of mpv17 results in loss of iridophores due to mitochondrial dysfunction in tilapia
• Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish. [europepmc]
• Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome. [europepmc]
• Function Over Form: Modeling Groups of Inherited Neurological Conditions in Zebrafish. [europepmc]
• Selection for Mitochondrial Quality Drives Evolution of the Germline. [europepmc]
• Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells. [europepmc]
• Nucleoside supplementation modulates mitochondrial DNA copy number in the dguok -/- zebrafish. [europepmc]
• Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish. [europepmc]
• The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria. [europepmc]
• Transcriptome analysis of egg viability in rainbow trout, Oncorhynchus mykiss. [europepmc]
• Fishing in the Cell Powerhouse: Zebrafish as A Tool for Exploration of Mitochondrial Defects Affecting the Nervous System. [europepmc]
• Identification of ATP synthase α subunit as a new maternal factor capable of protecting zebrafish embryos from bacterial infection. [europepmc]
• Mitochondria in Embryogenesis: An Organellogenesis Perspective. [europepmc]
• Proteomics Analysis of Early Developmental Stages of Zebrafish Embryos. [europepmc]
• Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos. [europepmc]
• Sequencing and annotation of the complete mitochondrial genome of a threatened labeonine fish, Cirrhinus reba. [europepmc]
• Daily mitochondrial dynamics in cone photoreceptors. [europepmc]
• Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish. [europepmc]
• Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs. [europepmc]
• A highly conserved zebrafish IMPDH retinal isoform produces the majority of guanine and forms dynamic protein filaments in photoreceptor cells. [europepmc]
• Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities. [europepmc]
• Mitochondrial connections with immune system in Zebrafish. [europepmc]
• Cone photoreceptors transfer damaged mitochondria to Müller glia. [europepmc]
• Development and Functions of Mitochondria in Early Life. [europepmc]
• Mitochondrial dysfunction and oxidative stress contribute to cross-generational toxicity of benzo(a)pyrene in Danio rerio. [europepmc]
• Analysis of oxygen consumption rates in zebrafish reveals differences based on sex, age and physical activity recovery. [europepmc]