Antibiotic production by soil bacteria under aerobic and micro-oxic conditions

2024/12/04 by Cierra Paaaina-Daquioag, Disha Byadarahalli Mohan Kumar, Debra R. Kerr +2
Agricultural and Biological Sciences · Medicine · #Fungal Biology and Applications #Mycorrhizal Fungi and Plant Interactions

paper · doi:10.17912/micropub.biology.001440

openalex publication_date 2024/12/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27

Abstract

Antimicrobial resistance presents a significant global challenge, undermining the effectiveness of antibiotic therapies and complicating disease management. The origin and spread of antibiotic-resistance genes outpaces the antibiotic discovery process, highlighting an urgent need for new approaches. This study investigated the production of antibiotics by soil bacteria under aerobic and micro-oxic conditions as part of a course-based research experience designed to introduce undergraduates to the global antibiotic resistance crisis. Significant differences in the diameters of the zones of inhibition against three tester strains were observed under differing oxygen concentrations. Soil isolates were identified with 16S rRNA sequence analysis.

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